How Much Time to Wait Before Eating Shrooms Again

Mushroom Poisoning Syndromes

There are many different types of mycotoxins. Of 14 distinctive types of mushroom poisoning constitute worldwide, and then far about x distinctive patterns of reactions to mycotoxins have been observed in North America. Nevertheless, since near mushroom species are rarely eaten, many toxins are poorly documented and syndromes not all the same observed in North America may plough up as more than and more people experiment with eating wild mushrooms. NAMA maintains a case registry where yous may report instances of mushroom poisoning.

The following list is not exhaustive. It is presented hither for informational purposes, and should not exist considered an aid to diagnosis. The images are shown as examples only and should not exist used for identification. For emergency identification, delight consult our listing of volunteers.  If yous doubtable that y'all accept consumed a poisonous mushroom, contact a doc, or your local poisonous substance control center.

After the incident, assist document mushroom poisonings past submitting an online report to the NAMA Poison Case Registry.

It is important to file a written report, fifty-fifty if the issue was merely a gastrointestinal upset. NAMA tracks ALL mushroom poisonings.

The post-obit syndromes are addressed below (click on heading to go directly to that section):

  • Gastrointestinal Irritants
  • Muscarine
  • Isoxazole Derivatives (Muscimol, Ibotenic Acid, and relatives)
  • Amanitin (Amatoxins)
  • Gyromitrin
  • Delayed Kidney Impairment: Orellanine
  • Psilocybin, Psilocin, and other Indole Derivatives
  • Prompt Kidney Damage
  • Coprine and other Alcohol Induced Syndromes
  • Miscellaneous and Unknown Toxins

Gastrointestinal Irritants

The well-nigh frequent form of mushroom poisoning is caused by a wide diversity of gastrointestinal irritants. The symptoms usually appear within 20 minutes to four hours of ingesting the mushrooms, and include nausea, airsickness, cramps, and diarrhea, which normally pass after the irritant had been expelled. Severe cases may require hospitalization. Supportive treatment may include attempts to eliminate the irritants. In all cases where there has been vomiting and diarrhea, measures to replace lost fluids and electrolytes are important. Recovery is complete, though a bout with severe gastro-abdominal distress may put one off e'er eating mushrooms again! Of import: If the gastrointestinal distress begins 6 to 24 hours afterwards ingestion of the mushrooms, there is a possibility of a very serious toxicity from Amatoxins (meet Amanitin). GI onset of 4-11 hours with dumb kidney part could be due to Allenic Norleucine (2-amino-4,v-hexadienoic acid).  GI onset greater that 24 hours and upwards to 21 days could be due to Orellanine.

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Muscarine

Mushrooms: Inocybe species, Clitocybe rivulosa (dealbata), and several relatives, and certain scarlet-pored Boletus.

The symptoms commonly occur within 15-thirty minutes of ingestion, and are focused on the involuntary nervous organisation. They include excessive salivation, sweating, tears, lactation (in pregnant women), plus astringent airsickness and diarrhea. These symptoms may be accompanied by visual disturbances, irregular pulse, decreased blood pressure level, and difficulty breathing. Victims normally recover within 24 hours, but severe cases may result in death due to respiratory failure. Atropine is a specific antidote, but must exist administered by a doc. Dogs are particularly susceptible to the toxin muscarine.

Inocybe lanuginosa

Inocybe lanuginosa

Clitocybe rivulosa (dealbata)

Clitocybe rivulosa (dealbata)
Photo Credit Michael Beug

Boletus eastwoodiae

Boletus eastwoodiae
Photo Credit Michael Beug

Boletus pulcherrimus

Boletus pulcherrimus
Photograph Credit Michael Beug

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Isoxazole Derivatives (Muscimol, Ibotenic Acid, and relatives)

Mushrooms: Amanita aprica, A. alpinicola, A. chrysoblema (muscaria), A. crenulata, A. frostiana, A. gemmata, A. multisquamosa (pantherina) (syn. A. cothurnata), A. pantherinoides (pantherina), A. strobiliformus, Tricholoma muscarium.

Atropine is Not indicated in cases of poisoning past ibotenic acrid or muscimol. All of the mushrooms that contain ibotenic acid and muscimol too sometimes contain muscarine (a toxin that got the proper name muscarine because it was kickoff isolated from Amanita muscaria in the late 1800s). Thus, patients sometimes also suffer muscarinic symptoms as well as symptoms of ibotenic acid and muscimol poisoning. Nonetheless, atropine'south furnishings are close to those of ibotenic acid and its use is likely to exacerbate symptoms. In dogs, use of atropine with any of these species tin can easily cause death.

Symptoms appear within xxx minute to ii hours after ingestion, and terminal for several hours. Nausea and vomiting are quite common, but the principle effects are on the central nervous system: confusion, visual baloney, a feeling of greater strength, delusions and convulsions. Drowsiness is a mutual symptom, and many who ingest these mushrooms fall asleep and tin can non be roused. In rare cases the coma-like state tin can last for more than than 24 hours. This facet of the syndrome can exist especially frightening for the attending dr., as most cases involve patients who go far in this obviously asleep state. The resulting panicked reaction and overtreatment, generally produces no benefit to the patient. In humans, in that location are no reliably documented cases of death from toxins in these mushrooms in the past 100 years, though there is ane case where a camper froze to expiry while in the comatose state. Dogs and specially cats can die from these isoxazole toxins, though it is of import for the vet not to euthanize an beast even though the chances for recovery appear remote — once the animal awakens from the comatose state recovery is normally complete over the course of a calendar week or so.

Treatment of humans and animals is largely supportive. Measures to reduce feet tin include reassuring the patient that the furnishings are just temporary. If at that place has been extensive vomiting and diarrhea, measures to supersede fluids and electrolytes can speed recovery. Recovery is commonly spontaneous. To reiterate: Muscarine plays no documented clinical role in poisonings past Amanita muscaria or A. pantherinoides. Atropine is not indicated.

Amanita alpinicola

Amanita alpinicola
Photo Credit Michael Beug

Amanita aprica

Amanita aprica
Photo Credit Michael Beug

Amanita chrysoblema (muscaria)

Amanita chrysoblema (muscaria)
Photo Credit Michael Beug

Amanita chrysoblema (muscaria)

Amanita chrysoblema (muscaria)
Photo Credit Michael Beug

Amanita chrysoblema (muscaria)

Amanita chrysoblema (muscaria)
Photograph Credit Michael Beug

Amanita multisquamosa (pantherina)

Amanita multisquamosa (pantherina)
Photo Credit Harley Barnhart

Amanita pantherinoides (pantherina)

Amanita pantherinoides (pantherina)
Photograph Credit Michael Beug

Amanita pantherinoides (pantherina)

Amanita pantherinoides (pantherina)
Photo Credit Michael Beug

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Amanitin (Amatoxins)

Mushrooms: Amanita phalloides, A. ocreata (the Western Destroying Angel, 2 unnamed species), A. bisporigera (the Eastern Destroying Affections, a group of several like named look-alikes), Pholiotina (Conocybe) filaris, Galerina marginata (syn. Grand. autumnalis, G. venenata), G. castaneipes, Lepiotia castanea, L. helveola, Fifty. subincarnata (syn. L. josserandii) , L. brunneoincarnata, Fifty. brunneolilacea, and shut relatives.

Extremely Serious. The fatality charge per unit for Amanitin poisoning is near 50% without prompt, knowledgeable medical handling, but is about x% in the U.Due south. and Canada where good medical care is readily available. Amatoxins are doubly dangerous due to the fact that the symptoms are delayed for six to 24 hours after ingestion, by which time the toxins take been completely absorbed by the body and subsequently the initial state of gastric distress, the patient may appear to recover almost twenty-four hour period two or solar day three and be sent home. Monitoring of liver enzyme part is critical in cases of delayed onset GI distress!

Amanitins are a group of complex circadian polypeptides which damage tissues by inhibiting RNA synthesis inside each individual prison cell. Onset of symptoms manifests itself in four stages:

  • First stage is a latency period of half dozen to 24 hours after ingestion, in which the toxins are actively destroying the victim's kidneys and liver, but the victim experiences no discomfort.
  • 2nd phase is a menstruum of about 24 hours characterized by violent vomiting, bloody diarrhea, and severe abdominal cramps.
  • Third stage is a period of 24 hours during which the victim appears to recover (if hospitalized, the patient is sometimes released!)
  • Fourth stage is a relapse, during which kidney and liver failure oftentimes occurs, leading to decease. Patients may also "bleed out" and die due to the destruction of clotting factors in the blood. There may be more than one relapse.
If y'all take whatever reason to suspect that someone has ingested an amanitin-containing mushroom, DON'T Expect for symptoms to appear! There is no antidote for amanitin poisoning, and the best promise is to rush the person to the infirmary where the toxins can be removed before being fully absorbed into the body.

Seeking prompt medical treatment when amatoxin poisoning is suspected is critical. Since the symptoms (NOTE: in the most serious cases, severe diarrhea can begin in as trivial as half-dozen hours post ingestion) typically do not appear until 12 or more than hours after ingestion of an amatoxin containing species, activated charcoal to remove the toxins from the GI tract is ineffective. In all merely the most severe cases, aggressive IV fluid handling tin slowly flush the toxins from the system in the excreted urine. Liver enzymes levels and claret clotting factors must exist closely monitored. In astringent cases (equally measured by liver enzyme levels and blood clotting factors)  experimental use of 4 silibinin and other measures may assistance enough that a liver transplant tin can be avoided. Apply of penicillin is no longer considered effective. Recently the internet has been filled with sites recommending use of thioctic acrid (alpha-lipoic acid) for treatment of amatoxin poisoning. It is ineffective. Many sites besides recommend using oral milk thistle excerpt (silibinin). Silibinin is not appreciably absorbed orally and is as well ineffective. For a full review of treatment strategies encounter "Amatoxin Poisoning in North America 2015-2016"

Amanita bisporigera group

Amanita bisporigera group
Photograph Credit Michael Beug

Amanita bisporigera group

Amanita bisporigera group
Photo Credit Michael Beug

Amanita ocreata

Amanita ocreata
Photo Credit Kit Scates

Amanita ocreata

Amanita ocreata
Photograph Credit Michael Beug

Amanita phalloides

Amanita phalloides
Photo Credit Michael Beug

Amanita phalloides

Amanita phalloides
Photo Credit Kit Scates

Amanita phalloides

Amanita phalloides
Photo Credit Michael Beug

Galerina castaneipes

Galerina castaneipes
Photograph Credit Michael Beug

Galerina marginata (autumnalis)

Galerina marginata (autumnalis)
Photo Credit Michael Beug

Lepiota subincarnata

Lepiota subincarnata
Photo Credit Michael Beug

Pholiotina (Conocybe) filaris

Pholiotina (Conocybe) filaris
Photo Credit Kit Scates

Pholiotina (Conocybe) rugosa

Pholiotina (Conocybe) rugosa
Photograph Credit Kit Scates

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Gyromitrin

Mushrooms: Gyromitra esculenta,G. ambigua, Thousand. infula, Cudonia circinans. Note Several additional Gyromitra spp., notably G. montana, Yard. gigas, G. fastigiata (=brunnea), Chiliad. californica, G. sphaerospora and also many related Ascomycetes, such as some species of Helvella, Verpa, and Cudonia spp., even Morels tin cause upset if consumed raw or not thoroughly cooked, the toxins are unknown, but gyromitrin has not been detected in any of these species.

Gyromitrin'due south product of hydrolysis is monomethylhydrazine (MMH), a colorless, volatile, highly toxic, carcinogenic compound, offset discovered and used for information technology'south hypergolic properties in combination with nitrogen tetroxide. MMH is used past NASA as rocket fuel, which should give some thought of what is meant past "volatile".

"Volatile" besides means that gyromitrin has a low boiling point, and thus mushrooms containing it can have a puzzling non-outcome on some, whereas others are severely poisoned. In Europe, it has sometimes but been the cooks who have died from Gyromitra esculenta. The dividing line between a "prophylactic and "lethal dose" is very slim.

Symptoms appear within two to 24 hours and include headaches, abdominal distress, astringent diarrhea, and vomiting. In astringent cases, liver, kidney, and cerise claret cell damage may occur, possibly resulting in death. Treatment is largely supportive, and a physician should be consulted.

Gyromitrin is too a known carcinogen, so consuming a less than toxic dose may also cause trouble down the line.

Gyromitra cf ambigua

Gyromitra cf ambigua
Photo Credit Michael Beug

Gyromitra esculenta

Gyromitra esculenta
Photograph Credit Michael Beug

Gyromitra esculenta

Gyromitra esculenta
Photo Credit Michael Beug

Gyromitra esculenta

Gyromitra esculenta
Photo Credit Michael Beug

Gyromitra infula

Gyromitra infula
Photo Credit Michael Beug

Cudonia circinans

Cudonia circinans
Photograph Credit Michael Beug

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Delayed Kidney Damage: Orellanine

Mushrooms: Aeronius (Cortinarius) orellanus, A. rubellus (=A. orellanoides, A. speciosissimus, A. rainierensis).

Extremely Serious. Onset of symptoms from orellanine poisoning tin can be very greatly delayed (as much every bit three weeks), the toxin isn't very well understood, and specific treatments are not available. A 1975 Finnish newspaper had incorrectly reported that dried Cortinarius gentilis caused severe harm when fed to rats, but their identification of C. gentilis was incorrect and later studies showed that C. gentilis does not contain orellanine. The first orellanine poisoning in Due north America involved kidney failure in a Michigan woman who consumed a Cortinarius species like to Aeronius (Cortinarius) orellanus simply found under oaks in 2008. In 2010 this new species was named Aeronius (Cortinarius) orellanosus. The second known Northward American orellanine case (2020) involved a Quebec man who consumed Aeronius (Cortinarius) rubellus from a sphagnum bog. Synonyms of A. rubellus include Aeronius (Cortinarius) rainierensis, Aeronius (Cortinarius) speciosissimus, and Aeronius (Cortinarius) orellanoides.

Symptoms occur within 36 hours to iii weeks of ingestion (boilerplate is nearly 8 days), and include nausea, vomiting, lethargy, anorexia, frequent urination, burning thirst, headache, sensations of coldness and shivering (fever more often than not absent), evidence or progressive kidney failure.

Across the standard management of kidney failure, there is little simply supportive treatment of utilize in cases of orellanine poisoning. Patients with astringent, only not irreversible harm may brainstorm to recover kidney function between two and four weeks after the onset of symptoms. NOTE: The compounds involved in this syndrome show a very strong uv fluorescence. Both the mushrooms and tissues of the poisoned individual will showroom this fluorescence.

Cortinarius gentilis

Cortinarius gentilis
Photo Credit Michael Beug

Aeronius (Cortinarius) rubellus

Aeronius (Cortinarius) rubellus
Photo Credit Christie Robertson

Aeronius (Cortinarius) rubellus

Aeronius (Cortinarius) rubellus
Photo Credit Christie Robertson

Aeronius (Cortinarius) rubellus

Aeronius (Cortinarius) rubellus
Photograph Credit Michael Beug

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Psilocybin, Psilocin, and other Indole Derivatives

Mushrooms: About 20 Psilocybe species including P. cyanescens, P. stuntzii, P. cubensis, and P. semilanceata, several Panaeolus species including P. cyanescens and P. subbalteatus, at least 3 Gymnopilus species most notably Gymnopilus spectabilis plus at least 1 Mycena, one Pluteus, one Conocybe and one Inocybe.

These indoles are well-known as hallucinogens, and these mushrooms have played important roles in faith and medicine in some parts of the world, notably in Southward America. Their properties were "rediscovered" by mycologists in Oaxaca in the 1930s, and studied by mycoethnographers Gordon and Valentina Wasson in the 1950s; their chemistry was documented past Albert Hoffmann.

Both psilocybin and psilocin are found naturally in mushrooms, though their ecological purpose is unknown. In the human body, they impact the serotonergic systems in the brain, and bear witness some cross-tolerance with substances such as LSD.

Onset of symptoms normally occurs within an hr of ingestion, and effects typically last up to four to six hours. Furnishings are primarily psychological and perceptual, including heightened color perception, emotional furnishings such as religious ecstasy or anxiety, and sometimes hallucinations or delusions. Equally with whatever other psychologically-active substance, mindset and situation tin can greatly influence psilocybin's subjective effects. Care should be taken non to affright or upset a person under its influence, and if a victim does become anxious, to reassure them that the effects are temporary. Piffling research has been done on antitoxins, but tryptophan may have a mitigating outcome.

Nausea and vomiting are sometimes associated, but by and large occur earlier than the psychological effects, and may exist associated with other toxins present in some psilocybin-bearing species, rather than with the indoles themselves. A very few severe reactions, including fevers and deaths, have been reported in contexts of psilocybin poisoning of small children; "grazing" accidents by toddlers should be treated in a infirmary.

Maybe the greatest danger posed by psilocybin as a mycotoxin is that the mycologically ignorant may, in hunting for "magic mushrooms," find themselves consuming something different and far more dangerous. Galerina marginata (Syn. M. autumnalis) and other amanitoxin-bearing "little brown mushrooms" may be mistaken for hallucinogenic species. At that place has fifty-fifty been a study of children inhaling the spores of Lycoperdon puffballs in the hopes of "getting high," only to wreak havoc on their lungs.

Gymnopilus luteofolius

Gymnopilus luteofolius
Photograph Credit Harley Barnhart

Psilocybe cubensis

Psilocybe cubensis
Photo Credit Michael Beug

Psilocybe cyanescens

Psilocybe cyanescens
Photo Credit Michael Beug

Psilocybe semilanceata

Psilocybe semilanceata
Photo Credit Michael Beug

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Prompt Kidney Damage

Mushrooms: Amanita smithiana. Note: A compound, chlorocrotylglycine, may as well exist toxic.

Amanita smithiana has caused numerous poisonings in the Pacific Northwest, where it is perchance being mistaken for the popular Matsutake, or "Pine Mushroom" Tricholoma murrillianum, to which it bears a superficial resemblance. Many physicians have been quick to aspect these poisonings to orellanine, and indeed there are some obvious similarities in the symptoms. However, onset of symptoms is more than rapid in cases of A. smithiana poisoning (between 4 and 11 hours, compared to orellanine with a 36 hour to three week onset period). A. smithiana causes gastrointestinal distress, anxiety, chills, cramps, disorientation, kidney failure and sometimes malaise, sweating, weakness, warm feeling, oliguria, polyurea, thirst. Amanita proxima and Amanita pseudoporphyria are suspected of containing the same toxins but these species have non yet been found in Northward America. To be safe, avert any North American Amanita resembling Amanita smithiana. Both allenic norleucine (two-amino-4,5-hexadenoic acrid) and chlorocrotylglycine are suspected as the toxic agents.

Amanita smithiana

Amanita smithiana
Photo Credit Michael Beug

Amanita smithiana

Amanita smithiana
Photo Credit Michael Beug

Amanita smithiana

Amanita smithiana
Photo Credit Michael Beug

Amanita smithiana

Amanita smithiana
Photo Credit Michael Beug

Immune-mediated hemolytic anemia. Mushroom: Paxillus involutus complex.

A complex of Due north American species that resemble the European species, Paxillus involutus, have caused poisonings in Northward America. It is the tertiary almost common cause of gastrointestinal symptoms in Eastern Europe, where is has a long and unfortunate culinary history. However, the main toxic component in P. involutus causes astute immune-mediated hemolytic anemia.

Hemolytic anemia occurs mainly in individuals who have eaten P. involutus for many years without ill effect. Because the syndrome is related to repeat, long-term exposure to the toxin, poisonings may likely go unrecognized, with the more than likely diagnosis being idiopathic immune hemolytic anemia.

It is perhaps warranted to suggest that in cases of idiopathic anemia, especially in patients of Eastern European extraction, that the question of P. involutus consumption be raised.

Paxillus involutus group

Paxillus involutus
Photograph Credit Tim Sage

Paxillus cuprinus

Paxillus cuprinus
Photograph Credit Michael Beug

Paxillus involutus group

Paxillus involutus grouping
Photo Credit Michael Beug

Paxillus vernalis

Paxillus vernalis
Photo Credit Michael Beug

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Coprine

Mushrooms with coprine: Coprinopsis atramentaria (=Coprinus atramentarius), C. insignis, C. quadrifidus, C. variegata.

Onset of Antabuse-similar symptoms may begin a few minutes later on alcohol is consumed past a person who has typically eaten Inky Caps (Coprinopsis atramentaria). The symptoms are tachycardia (racing eye) and palpitations, tingling arms and legs, warmth and flushing, and sometimes headache, heavy limbs, salivation. Even alcohol consumption as much as five days afterwards eating Inky Caps tin trigger the Antabuse-like reaction. Coprine has been shown to be highly carcinogenic and thus avoidance of Coprinopsis atramentaria is wise even for people who do not consume alcohol.

Coprinopsis atramentaria

Coprinopsis atramentaria
Photo Credit Michael Beug

Coprinopsis atramentaria

Coprinopsis atramentaria
Photo Credit Harley Barnhart

Coprinopsis atramentaria v acuminata

Coprinopsis atramentaria 5 acuminata
Photograph Credit Kit Scates

Other Alcohol-Induced Syndromes

Mushrooms: Coprinus comatus, Ampulloclitocybe (Clitocybe) clavipes, Suillellus (Boletus) luridus, Morels, Pholiota squarrosa, Armillaria mellea group, Pleurotus ostreatus group, Boletus edulis, etc.

Symptoms include GI distress in susceptible individuals. The delay is upward to 5 hours. However, this is non the Antabuse syndrome (see above) of the Inky Cap involving racing eye, warmth and flushing, etc.

Ampulloclitocybe clavipes

Ampulloclitocybe (Clitocybe) clavipes
Photo Credit Michael Beug

Coprinus comatus

Coprinus comatus
Photograph Credit Michael Beug

Morchella species

Morchella species
Photo Credit Michael Beug

Pholiota squarrosa

Pholiota squarrosa
Photo Credit Michael Beug

Pleurotus ostreatus group

Pleurotus ostreatus group
Photo Credit Michael Beug

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Miscellaneous Syndromes

Chlorophyllum molybdites

Chlorophyllum molybdites, The green-spored parasol, is the most common mushroom crusade of man poisonings in North America leading to astringent gastro-intestinal distress, sometimes with blood in the vomitus and excrement.
Pets tin likewise be poisoned. Be alert to keep any mushrooms that grow in your m picked and disposed of (the mushrooms are prophylactic to pick upwardly and throw away). For both humans and pets, intravenous rehydration therapy is nearly important, with whatsoever other symptoms treated on a symptomatic basis.

Chlorophyllum molybdites

Chlorophyllum molybdites
Photo Credit Kit Scates

Chlorophyllum molybdites

Chlorophyllum molybdites
Photograph Credit Kit Scates

Chlorophyllum molybdites

Chlorophyllum molybdites
Photo Credit Kit Scates

Chlorophyllum molybdites

Chlorophyllum molybdites
Photograph Credit Kit Scates

Omphalotus species

The jack-o-lanterns in North America include Omphalotus illudens and Omphalotus subilludins in the east and Omphalotus olivascens in the west. These species are bioluminescent. The toxin was long thought to be muscarine, merely the symptoms do not match classical muscarinic poisoning. The toxins include the sesquiterpines illudin M and illudin Due south. Generally, ane to three hours after a repast, the victim will endure nausea (xc% of cases) and vomiting (73% of cases) with abdominal pain, headache, feelings of burnout, weakness (forty%) and dizziness. At times there will be sweating and salivation (15%), diarrhea (22%). At that place may be a lingering bitter sense of taste. Recovery is usually rapid with almost victims recovered inside 12 hours. Usually the victims idea that they were picking Chanterelles.

Omphalotus illudens (olearius)

Omphalotus illudens (olearius)
Photo Credit Harley Barnhart

Omphalotus illudens

Omphalotus illudens
Photo Credit Kit Scates

Omphalotus olivascens (Western illudens)

Omphalotus olivascens (Western illudens)
Photograph Credit Michael Beug

Rhabdomyolysis. Mushrooms: Tricholoma equestre complex (=T. flavovirens), Russula subnigricans.

Toxicity from Tricholoma equestre complex has not been reported from the U.S. and some question whether or not it is unsafe, only consumption of massive quantities of this species in Europe take reportedly resulted in delayed kidney damage, delayed neurotoxicity, and breakdown of muscle fibers with release of myoglobin into the blood stream. The European cases of rhabdomyolysis are associated with respiratory and cardiac (myocarditis) complications leading to death. Myocarditis is an inflammation of the heart muscle. The rhabdomyolysis observed with Russula subnigricans in Nippon and Taiwan occurs by a different mechanism than that observed with Tricholoma equestre complex. In North America, several dissimilar Tricholoma species have been known as Tricholoma equestre complex. Some are delicious and some accept a very nasty gustatory modality. Russula subnigricans is a blackening Russula in the compactae clade. It is probably wise to avoid all North American blackening Russula species.

Tricholoma equestre group

Tricholoma equestre grouping
Photograph Credit Michael Beug

Tricholoma equestre group

Tricholoma equestre group
Photograph Credit Michael Beug

Tricholoma equestre var. equestre group

Tricholoma equestre var. equestre group
Photo Credit Michael Beug

Erythromelalgia. Mushrooms: Clitocybe amoenolens and C. acromelalgia. Similar species include Clitocybe (Lepista) inversa, Clitocybe squamosa, Clitocybe gibba, and Hygrophoropsis aurantiaca.

While we have no cases reported for N America, Saviuc and Danel (Saviuc P, Danel V, "New Syndromes in Mushroom Poisoning." Toxicol Rev 2006; 25(3):199-209) signal out that the erythromelalgia syndrome was described as early as the 19th century in Japan and Republic of korea with Clitocybe acromelalga and since 1996 in France and after in Italy with Clitocybe amoenolens. Erythromelalgia occurs every bit a consequence of a maldistribution of blood menstruum with extremities of the trunk (typically nose, fingers and toes) calling for more blood and winding up with so much blood menstruation through various open up vessels that easily and feet and nose receive too much and turn bright cerise, warm to the touch. The situation is very painful and symptoms tin terminal for months. Onset of symptoms is about 1 week afterward ingestion of the mushrooms and appears to be caused by acromelic acids, compounds that structurally mimic the neurotransmitter glutamate.

Clitocybe amoenolens

Clitocybe amoenolens

Encephalopathy. Mushrooms: Hapalopilus rutilans (=Hapalopilus nidulans), Pleurocybella porrigens

Hapalopilus nidulans and Hapalopilus rutilans (Index Fungorum lists both species, but genetic work seems to betoken that they are synonymous) can contain upward to 40% by dry out weight polyporic acrid (a dihydroxyquinone derivative). Polyporic acid reacts with KOH to give a diagnostic red to lilac to purple color. Hapalopilus nidulans is a small, fleshy, drab orangish polypore (sometimes with pale pinkish tones) establish on hardwoods in eastern North America and reported to occur on conifers in western North America. Whether the western material is the same species equally the eastern material is unclear, just the KOH exam indicates the probable presence of polyporic acid (though in that location are other compounds that can give a false positive reaction). Ingestion of this species tin cause kidney dysfunction and brain damage.

In Japan in 2004 ingestion of large amounts of Pleurocybella porrigens led to an outbreak of convulsive encephalopathy in patients with a history of chronic renal failure resulting in over a dozen deaths. To see a longer treatment of this finding, follow this link...

Hapalopilus rutilans (=Hapalopilus nidulans)

Hapalopilus rutilans (=Hapalopilus nidulans)
Photo Credit Dan Molter

Pleurocybella porrigens

Pleurocybella porrigens
Photo Credit Michael Beug

Pleurocybella porrigens

Pleurocybella porrigens
Photo Credit Michael Beug

Rash. Suillus sp. and sometimes other mushrooms

Simply treatment mushrooms can on rare occasion cause a rash and itching similar to reaction to poisonous substance oak and poison ivy in sensitive individuals. Reported most frequently for Suillus americanus and like species.

Suillus americanus

Suillus (Boletus) americanus
Photo Credit Michael Beug

Suillus flavidus

Suillus (Boletus) flavidus
Photograph Credit Michael Beug

Shiitake Dermatitis Syndrome – Toxic and Allergic Reactions to Raw and Undercooked Shiitake

For affected individuals, a rash usually begins about 48 hours after consumption of raw or undercooked Shiitake and lasts for nearly 10 days. It is a toxic, not an allergic, reaction and is believed to event from lentinan, a starch-like polysaccharide, triggering blood vessels to amplify and leak pocket-size amounts of inflammatory compounds just beneath the pare. The rash typically begins as red areas that neither hurt nor itch. Before long red blisters course then harden over the red regions but the rash is non initially itchy like a poisonous substance oak rash would be at that point. The ruby streaks so plough to purple raised welts which persist for days. The purple welts make the victim appear to accept been flogged or to accept been vigorously scratching a poison oak rash. The syndrome was long thought to be restricted to Asia since nearly of the world's production of Shiitake [Lentinula edodes (Berk.) Pegler] occurs in Asia. However, a case has recently been reported from Portland, Oregon and there may take been other cases that were non diagnosed. Clinically the rash resembles flagellate dermatitis caused by Bleomycin, a sulfur-containing polypeptide derived from Streptomyces verticillus. Lentinan is decomposed upon heating so it is only consumption of raw or partially cooked Shiitake that poses a problem. Only ii% or less of the population is likely to exist afflicted.

While Shiitake dermatitis itself is a toxic reaction, not an immune-stimulated allergic reaction, consumption a large amounts of raw Shiitake in individuals who would otherwise be unaffected, can lead to an allergic response. Sensitized individuals react strongly when pricked with raw Shiitake but not with cooked Shiitake, indicating that they take developed an allergy. Some workers in Shiitake grow houses develop an eczema-similar rash due to Shiitake specific immunoglobulin. At that place are too documented cases of allergic and chronic hypersensitivity pneumonitis induced by spores of Shiitake.

Shiitake flagellate dermatitis has become so common in North America, that most doctors now immediately recognize the syndrome and know the best treatments.

Lentinula edodes

Lentinula edodes
Photo Credit Michael Beug

Claret Thinning.
Mushrooms: Many Auricularia species

Consumption of cooked Auricularia species can upshot in purplish bruises (Szechuan purpurea), excessive haemorrhage for menstruating women, and excessive bleeding for people on blood thinners.

The species involved are known as "wood ears" among numerous other common names. They are popular for texture (not flavor) in many Asian dishes.

Auricularia

Auricularia sp.
Photo Credit Michael Beug

Auricularia

Auricularia sp.
Photo Credit Michael Beug

Auricularia

Auricularia sp.
Photograph Credit Harley Barnhart

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Source: https://namyco.org/mushroom_poisoning_syndromes.php

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